A REVIEW OF CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most recently, it's been discovered that conolidine and the above derivatives act around the atypical chemokine receptor 3 (ACKR3. Expressed in comparable places as classical opioid receptors, it binds to the big range of endogenous opioids. In contrast to most opioid receptors, this receptor functions to be a scavenger and doesn't activate a next